BioRevolution: From Genes to Global Solutions is a comprehensive volume that explores the transformative impact of biotechnological advances across multiple domains. The book is structured into five key sections, each addressing a critical aspect of the ongoing BioRevolution. It begins with a foundation in genomics, genetic diversity, and systems biology, setting the stage for understanding the latest breakthroughs in crop production and the hidden complexities of the genome. The text then delves into nanobiotechnology and advanced therapeutic engineering, highlighting innovations in precision medicine, intelligent nanocarriers, targeted drug delivery, and the engineering of CAR T-cells for cancer therapies.

Moving forward, the book addresses precision health, personalized nutrition, and the pivotal role of the human microbiome in disease prevention and health optimization. It examines the development of biofortified foods, strategies to combat antimicrobial resistance, and the search for climate-resilient probiotics. Furthermore, the volume discusses sustainable agriculture through the lens of nano fertilizers and climate-responsive biotechnologies, presenting solutions for modern and environmentally conscious food production systems.

The final section focuses on environmental biotechnology and the circular bioeconomy, showcasing cutting-edge approaches to pollution remediation, the use of ionic liquid-modified nanomaterials, and innovative methods for plastic degradation using insect-associated gut microbiomes. Overall, this book provides a holistic view of how biotechnological innovations are shaping sustainable solutions for health, agriculture, and the environment on a global scale.

Vision and Editorial Perspectives

1. Bio-revolution: From Genes to Global Solutions in Crop Production 2025/2052 and Beyond
   Manfred J. Kern
2. The Unread Genome: Decoding Biology’s Dark Matter
   Sarangdhar Nayak, Mohit Garg, Uma Maheswara Rao Chanchala, Sandeep K. Saxena and Pawan K Dhar
3. Engineering CAR-T Cells as Living Drugs: Insights from Hematologic Malignancies and Ovarian Cancer
   Vanshika Kumar and Manoj Kumar Kashyap

SECTION I: Molecular Foundations of the BioRevolution: Genes, Genomes, and Intelligent Nanodesign

1. Nanobiotechnology and Precision Medicine: Engineering Intelligent Nanocarriers for Targeted Therapeutic Delivery and Tumor Microenvironment Remodeling
   Aaryaa Singh, Sudiksha Jaiswal, Vikash Sharma, Vaishnavi Eknath Shinde, Pankaj Malhotra, Gunjan Sharma, Ashish Kumar, Machiavelli Singh and Arun K. Sharma
2. Nanobiotechnology and Advanced Therapeutics ? Nanomaterials for Therapeutics ? Smart Drug Delivery Mechanism
   Md. Momina Shanwaz and Shyam Perugu
3. Nanoparticle-Based Drug Delivery Systems for Targeted Cancer Therapy
   Nidhi Choudhary, Abhisht Tripathi and Kunal
4. Cytogenetic Abnormalities in Acute Myeloid Leukemia with Myelodysplasia-Related Changes (AML-MRC)
   Rishabh Pandey, Munindra Ruwali and Sangeeta Kumari

SECTION II: Precision Health and Personalized Therapeutics

1. Targeted Drug Delivery to the Different Challenging Sites of the Body
   Lubna Nazir Zoha, Rishika Gupta and Anil Kumar
2. Engineering the Human Microbiome for Precision Health: Multisystem Integration and Therapeutic Reprogramming
   Sudiksha Jaiswal, Aaryaa Singh, Vikash Sharma, Vaishnavi Eknath Shinde, Pankaj Malhotra, Gunjan Sharma, Ashish Kumar, Machiavelli Singh and Arun K. Sharma
3. Dynamics of Vaginal Microflora: A Biotechnology Perspective
   Sheetal Chandela, Munindra Ruwali, B Shanmugasundaram and Sangeeta Kumari
4. Precision and Personalized Medicine and Nutrition
   Aarti, Naveen K Kaushik and Roji Devi

SECTION III: Bioengineered Nutrition, Probiotics, and Food-System Innovation

1. Biofortified Food and Health: Bridging the Gap Between Food Production and Public Health
   Seema Sonkar and Shubhi Srivastava
2. Role of Phages and Oral Enzymes in Combating Antimicrobial Resistance Within the Gut
   Shruti Ahlawat and Deepali Rustagi
3. Genome-Driven Discovery of Climate Resilient Probiotics for Future Preservation Systems
   Tanisha Gogna, Pooja Sharma and Gagandeep Kaur
4. Nano Fertilisers Versus Conventional Fertilisers: A Sustainable Perspective to Modern Agriculture
   Manisha Lohchab and Babita Khosla

SECTION IV: Planetary Biotechnology and the Bioeconomy: From Climate Action to Global Competitiveness

1. Biotechnology for Climate Change Mitigation
   Rekha, Jayanti Tokas, Nisha Kumari, Shivangi Bishnoi, Manju Rani and Shikha Yashveer
2. From Pollution to Solution: Harnessing Biotechnology for Environmental Sustainability
   Vibhu Bhatia and Neharika Sawant
3. Ionic Liquid Modified Nanomaterials and their Application in Environmental Remedies
   Mohd. Jamshaiya Raza and Chandra Mouli Pandey
4. Exploring the Role of Insect-Associated Plastic Degradation and their Gut-Microbiome Action as Biocatalysts
   Mansi Sharma, Shruti Ahlawat and Sakshi Sharma
5. Biotechnology in India: Science-Led Bioeconomic Competitiveness
   Pardeep Kumar, Kunal and Machiavelli Singh